App 02 · Literature Monitoring

Consolidated literature surveillance with deterministic triage.

Scan PubMed and local journals on one schedule, then triage with a transparent, self-learning engine — explainable decisions a reviewer can trust, not an opaque verdict. Qualifying articles flow toward structured ICSR / E2B(R3) drafting.

Vigicore LiteratureIllustrative
LiteratureTriage queue
Triage queue
New search
Live · PubMed + Embase · 142 screened today · last sync 05:40
In scope 0Needs review 0Excluded 0
Drug-induced liver injury with Brevanta: a case series
PubMed · 2026
94
score
In scope
Spontaneous QT-prolongation reports with Caldyra
Embase · 2026
88
score
In scope
Cost-effectiveness of pharmacovigilance monitoring programmes
PubMed · 2025
41
score
Needs review
Population pharmacokinetics of Orvexa in renal impairment
PubMed · 2026
19
score
Excluded
Article detailRelevance 94

Drug-induced liver injury with Brevanta: a case series

PubMed · 2026 · case report · PMID 41284417

A 58-year-old developed elevated transaminases and jaundice after six weeks of Brevanta; dechallenge led to recovery and rechallenge was positive, suggesting a probable drug-related hepatic reaction.

Auto-coded to MedDRA
ReactionPTSOC
Liver injuryHepatocellular injuryHepatobiliary disorders
Triage confidence94%
Suspect drug matchedReportable reactionCase report
Confirm in scopeReclassify
Coded by triage engine · confirmed by A. Khan · ready for ICSR / E2B(R3) draft
Why deterministic?

Every triage decision is rule-driven, auditable, and improves from reviewer feedback — so accuracy grows without sacrificing explainability or control.

In pharmacovigilance, a reviewer needs to know why an article was prioritised. Vigicore's triage is transparent by design: the reasoning is inspectable, the rules learn from your decisions, and nothing is hidden behind an unexplained model output.

How it works

Scope → Scan → Triage → Report.

Step 1

Scope

Define products, search profiles, and journal sources per client or programme.

Step 2

Scan

PubMed and local journals are surveyed on schedule; results are consolidated in one queue.

Step 3

Triage

The deterministic engine ranks and classifies articles with explainable, auditable reasoning.

Step 4

Report

Code reactions to MedDRA and move qualifying cases toward ICSR / E2B(R3) drafting.

Capabilities

Surveillance to reporting, on one platform.

Consolidated scanning

PubMed plus local / regional journal sources surveyed in one place, on your schedule and scope.

Deterministic triage

A transparent, rule-driven engine that learns from reviewer feedback — explainable decisions, not a black-box LLM verdict.

MedDRA coding

Extracted reactions auto-coded to LLT / PT and rolled up to SOC from the shared OnePV dictionary.

ICSR / E2B(R3) support

Structured drafting support to move qualifying articles toward E2B(R3) reporting.

Review-ready line listings

Clean, exportable line listings and a triage queue built for reviewer sign-off.

Tenant-scoped surveillance

Per-client scopes, products, and search profiles within the shared platform.

Get in touch

Map Literature Monitoring to your scope.

Tell us your products, regions, and journal sources, and we'll walk through how consolidated scanning and deterministic triage fit your surveillance obligations.

Seeking investment

Signal Automation and Literature Monitoring are live and growing. We're seeking strategic investment and enterprise partnerships to scale OnePV.

Read the investment story →
0 / 20 min

We respond to qualified PV, enterprise, and investment enquiries.